Last year the Bicuspid Aortic Foundation participated in the invitation from the NHLBI for public input into strategic research topics for the next 10 years. Preliminary topics were announced previously. We have now been notified of the final decisions.
|Critical Challenge||In patients with an aortic aneurysm, better tools are needed to determine which patient phenotypes and disease characteristics could best predict who would benefit from a repair. Examples of such tools include animal models that reflect human pathology and biomarkers/molecular imaging tools that are predictive of rupture or dissection.(4.CC.02)|
|Compelling Question||What is the optimal clinical management approach for patients with severe calcific aortic stenosis but with minimal symptoms?(5.CQ.09)|
This question must be answered, and it is within reach to do so. It is beyond description to lose the otherwise healthy who have BAV and diagnosed aortic valve disease. This topic speaks directly to what happened to Chuck Doherty. Chuck's family is not the only one we have met who have suffered sudden loss due to this. We would like to see aortic regurgitation addressed also, but this is a start!